Development status and analysis of pharmaceutical glass packaging market II
II. Water injection packaging
water injection packaging is mainly glass ampoules. At present, the annual demand of the domestic market is 29billion tubes, and there are many domestic manufacturers. The pharmaceutical industry began to force the elimination of non folding ampoules in 1990, but the problem of easy folding ampoules is still prominent at present. The purpose of carrying out the easy break ampoule is to make the ampoule easy to break, so as to avoid the glass particles formed by filing into the liquid medicine when the ampoule is used. Research shows that once glass particles enter the human body with the liquid medicine, they will have serious consequences. In addition, the victims also include medical staff. During injection, ampules are not easy to break and are cut frequently, which brings great hidden dangers and threats to the safety of medication and the use of medical staff. The important reasons for the above problems are: first, the low level of product standards; Second, the product quality, ampoule wall thickness and breaking force indicators are not up to the requirements. In addition, some small and medium-sized enterprises and pharmaceutical enterprises ignore social benefits and ignore ampoule quality and drug safety, which contributes to the emergence of low-quality and low-level competitive marketing in the ampoule Market
according to market research and analysis, it is predicted that China's pharmaceutical injections will increase at a rate of 5% per year, and the output will reach 37.5 billion tubes in 2010. 10% - 15% of the injections need ampoules that are resistant to strong acids, strong alkalis and light, and 5% of the ampoules need high-quality printing
III. infusion bottle
at present, the drug packaging containing infusion agent is still mainly glass infusion bottle. This product is widely used because of its good air tightness, cleanness and transparency, not easy to deteriorate and many other advantages. However, the reuse of glass infusion bottles has become a major problem that threatens people's safe medication
China's pharmacopoeia requires that the water resistance of the inner surface of glass bottles used for infusion for injection must meet the requirements of grade HC1 and HC2 in gbl2416.1 (iso4802 is equivalent to this standard). There are two kinds of glasses that meet this requirement: one is borosilicate glass with 10% boron oxide (B203), referred to as type I glass, which has excellent chemical stability. At present, there is no infusion bottle made of this kind of glass in China, and there are not many infusion bottles made of this kind of glass in the world. The other is sodium calcium silicate glass with internal surface treatment, which is called turn glass for short. Its internal surface has a very thin silicon rich layer, which can achieve the effect of type I glass. It is certainly important to adopt for the extensive product transformation in the world. At present, one third of infusion bottles in China are made of this kind of glass, and the other two thirds are made of non-I and non-ii glass containing about 2% boron oxide B2O3). The test shows that the water resistance of type II glass is better than that of non type I and non type II glass, but type II glass is only dealkylated on the inner surface, forming an extremely thin silicon rich layer close to type I glass. If it is reused, due to the damage in the process of bottle washing and filling disinfection, the extremely thin silicon rich layer will be destroyed and the performance will decline. Therefore, it is clearly stipulated in the national standard gb2639, Type II glass is only applicable to disposable infusion bottles
at present, there is a big gap between the manufacturing quality level of domestic infusion bottles and similar international products, mainly in the light weight, cleanliness, packaging and appearance transparency, uniformity and so on
IV. the impact of the development trend of the pharmaceutical industry on pharmaceutical glass packaging
the pharmaceutical industry is internationally recognized as a "sunrise industry that will never decline", and human survival and health cannot be separated from medicine.) In recent years, the economic operation of China's pharmaceutical industry is full of stamina. Experts predict that by 2005, the demand for drugs in China will reach 2.1 billion yuan, a net increase of 94 billion yuan over 2000. The growth of the total population, the aging of the population structure and the migration of rural population to cities will be the three irreversible factors that will ensure the steady growth of the domestic pharmaceutical market. We can provide you with the basic technical conditions of the experimental machine. During the Tenth Five Year Plan period, China's rural pharmaceutical market will be rapidly expanded. It is predicted that it has played a key role in the safety, high-speed and heavy load of railway transportation. In 2010, the total consumption of drugs in rural areas is expected to reach 40billion yuan. There is no doubt that the broad rural pharmaceutical market will provide huge business opportunities for antibiotic generic drugs. The potential development space of China's pharmaceutical market plays a decisive role in the development and growth of pharmaceutical glass packaging
at present, China has become the second largest producer of bulk drugs in the world, and the output of antibiotics and vitamins is among the best in the world. China has been exporting a large number of antibiotic raw materials. In addition, the growth of the demand for imported drugs has been curbed, and the import volume of preparations has declined. The most affected is the imported antibiotics, whose market share has been replaced by garden drugs and "joint venture drugs". In addition, the high proportion of antibiotics used due to the abuse of antibiotics is common in Asian developing countries. Therefore, for a long time to come, the leading role of antibiotics is still generic drugs, which are of high quality and low price, It meets the needs of more than one billion Chinese people. As far as the glass bottles containing antibiotics are concerned, they will still show a steady growth trend. With the progress of society, the improvement of people's living standards and the accession to WT0, the proportion of the use of various new drugs, special drugs and high-end precious drugs will gradually increase. Such drugs will put forward higher demand for the upgrading and upgrading of pharmaceutical glass. This development trend can drive to improve the added value of pharmaceutical glass packaging products
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